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Eldepryl and Solriamfetol Hydrochloride

Determining the interaction of Eldepryl and Solriamfetol Hydrochloride and the possibility of their joint administration.

Check result:
Eldepryl <> Solriamfetol Hydrochloride
Relevance: 14.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.CONTRAINDICATED: Coadministration of solriamfetol with other drugs that also inhibit the reuptake of dopamine or norepinephrine, including monoamine oxidase inhibitors (MAOIs), may increase the risk of hypertensive reactions including death, stroke, myocardial infarction, aortic dissection, pulmonary edema, and renal failure. Additionally, MAOIs can increase dopaminergic and noradrenergic activity by inhibiting the metabolism of dopamine and norepinephrine. MANAGEMENT: Concomitant use of solriamfetol with MAOIs is considered contraindicated. At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with solriamfetol. References "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.

Professional:

CONTRAINDICATED: Coadministration of solriamfetol with other drugs that also inhibit the reuptake of dopamine or norepinephrine, including monoamine oxidase inhibitors (MAOIs), may increase the risk of hypertensive reactions including death, stroke, myocardial infarction, aortic dissection, pulmonary edema, and renal failure. Additionally, MAOIs can increase dopaminergic and noradrenergic activity by inhibiting the metabolism of dopamine and norepinephrine.

MANAGEMENT: Concomitant use of solriamfetol with MAOIs is considered contraindicated. At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with solriamfetol.

References
  • "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.
Eldepryl

Generic Name: selegiline

Brand name: Eldepryl, Zelapar, Emsam

Synonyms: Eldepryl Capsules

Solriamfetol Hydrochloride

Generic Name: solriamfetol

Brand name: Sunosi

Synonyms: Solriamfetol

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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