Elfolate and Glasdegib Maleate

• Generic Name: l-methylfolate
• Dosage Forms: n.a.
• Other Brand Names: Denovo, Deplin 15, Deplin 75, Elfolate, L-Methylfolate Formula 15, Zervalx, Vilofane-DP, Duleek-DP

• It is used to aid diet needs.

• Generic Name: glasdegib
• Dosage Forms: n.a.
• Other Brand Names: Daurismo

Glasdegib maleate is a hedgehog pathway inhibitor indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of intensive induction chemotherapy.

Glasdegib maleate has not been studied in patients with the comorbidities of severe renal impairment or moderate-to-severe hepatic impairment.