Emtricitabine and tenofovir and Trospium
Determining the interaction of Emtricitabine and tenofovir and Trospium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using trospium together with tenofovir may increase the blood levels and effects of both medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Theoretically, coadministration of trospium chloride with other drugs that are eliminated by active tubular secretion may result in increased plasma concentrations of trospium and/or the coadministered drug(s). The mechanism is competitive inhibition of renal excretion. Drugs that are thought to undergo active tubular secretion include acyclovir/valacyclovir, cidofovir, cimetidine, digoxin, flecainide, ganciclovir/valganciclovir, metformin, midodrine, morphine, pancuronium, procainamide, quinidine, ranitidine, tenofovir, triamterene, and vancomycin.
MANAGEMENT: Patients receiving trospium chloride in combination with other drugs that undergo active tubular secretion should be monitored for excessive pharmacologic effects of one or both drugs, and the dosages of the drugs adjusted if necessary.
- "Product Information. Sanctura (trospium chloride)." Odyssey Pharmaceutical, East Hanover, NJ.
Generic Name: emtricitabine / tenofovir
Brand name: AccessPak for HIV PEP Basic, Descovy, Truvada
Synonyms: Emtricitabine and Tenofovir Disoproxil Fumarate
Generic Name: trospium
Brand name: Sanctura, Sanctura XR, Regurin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Emtricitabine and tenofovir-Trospium Chloride
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- Emtricitabine and tenofovir-Trospium Tablets
- Emtricitabine and tenofovir-Trovan
- Emtricitabine and tenofovir-Troxyca ER
- Trospium-Emtricitabine and Tenofovir Alafenamide
- Trospium-Emtricitabine and Tenofovir Disoproxil Fumarate
- Trospium-Emtricitabine and Tenofovir Tablets
- Trospium-Emtricitabine Capsules
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- Trospium-Emtricitabine, lopinavir, ritonavir, and tenofovir