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Emtricitabine, nelfinavir, and tenofovir and Valium

Determining the interaction of Emtricitabine, nelfinavir, and tenofovir and Valium and the possibility of their joint administration.

Check result:

Emtricitabine, nelfinavir, and tenofovir <> Valium

Relevance: 19.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Nelfinavir may increase the blood levels and effects of diazePAM. This can increase the risk of side effects including excessive drowsiness and breathing difficulties. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Nelfinavir competitively inhibits the CYP450 3A4 isoenzyme and may interfere with the metabolism of some benzodiazepines.

MANAGEMENT: Caution is advised if benzodiazepines are administered with nelfinavir. Patients should be monitored for the possibility of potentially serious and/or life threatening events (e.g. prolonged sedation, respiratory depression) associated with the accumulation of these agents.

References

"Product Information. Viracept (nelfinavir)." Agouron Pharma Inc, La Jolla, CA.

Emtricitabine, nelfinavir, and tenofovir

Generic Name: emtricitabine / nelfinavir / tenofovir

Brand name: AccessPak for HIV PEP Expanded with Viracept

Synonyms: n.a.

What is Emtricitabine, nelfinavir, and tenofovir?

Valium

Generic Name: diazepam

Brand name: Valium, Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Zetran

Synonyms: n.a.

What is Valium?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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