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Emverm and Flagyl

Determining the interaction of Emverm and Flagyl and the possibility of their joint administration.

Check result:
Emverm <> Flagyl
Relevance: 06.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using metroNIDAZOLE together with mebendazole. Using these medications together may be associated with Stevens-Johnson syndrome. Stevens-Johnson syndrome is a severe form of an allergic reaction and rash. The rash can be generalized and can appear as lesions on the soles of the feet, palms and inside the mouth. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Limited clinical data have suggested that coadministration of metronidazole and mebendazole may be associated with Stevens-Johnson syndrome/toxic epidermal necrolysis. The mechanism is unknown.

MANAGEMENT: It is recommended that concomitant use of mebendazole and metronidazole should be avoided.

References
  • Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL: http://www.appco.com.au/appguide/default.asp." ([2006]):
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
Emverm

Generic Name: mebendazole

Brand name: Emverm, Vermox

Synonyms: n.a.

Flagyl

Generic Name: metronidazole

Brand name: Flagyl, FIRST Metronidazole, Flagyl 375, MetroGel

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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