Enasidenib Mesylate and Nifedical XL

• Generic Name: enasidenib
• Dosage Forms: n.a.
• Other Brand Names: Idhifa, Idhifa

For the treatment of relapsed or refractory AML with IDH2 mutation (designated an orphan drug by FDA for this use).

FDA-approved diagnostic test (e.g., Abbott RealTime IDH2 assay) required to confirm the presence of IDH2 mutation prior to initiation of therapy.

• Generic Name: nifedipine
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.