Enasidenib Mesylate and Otezla

• Generic Name: enasidenib
• Dosage Forms: n.a.
• Other Brand Names: Idhifa, Idhifa

For the treatment of relapsed or refractory AML with IDH2 mutation (designated an orphan drug by FDA for this use).

FDA-approved diagnostic test (e.g., Abbott RealTime IDH2 assay) required to confirm the presence of IDH2 mutation prior to initiation of therapy.

• Generic Name: apremilast
• Dosage Forms: tablet, film coated
• Other Brand Names: Otezla, Otezla Starter Pack

Otezla (apremilast) inhibits an enzyme within your immune system that can affect certain cells and contribute to inflammation in the body.

Otezla is used to treat the symptoms of active psoriatic arthritis in adults.

Otezla can relieve tenderness and swelling in and around the joints, but this medicine is not a cure for psoriatic arthritis.

Otezla is used to treat moderate to severe plaque psoriasis in people who may also receive phototherapy or other treatments for psoriasis.

Otezla is also used to treat adults with oral ulcers associated with Behçet’s Disease.