Enasidenib Mesylate and Oxaprozin Potassium

• Generic Name: enasidenib
• Dosage Forms: n.a.
• Other Brand Names: Idhifa, Idhifa

For the treatment of relapsed or refractory AML with IDH2 mutation (designated an orphan drug by FDA for this use).

FDA-approved diagnostic test (e.g., Abbott RealTime IDH2 assay) required to confirm the presence of IDH2 mutation prior to initiation of therapy.

• Generic Name: oxaprozin
• Dosage Forms: n.a.
• Other Brand Names: Daypro

Consider potential benefits and risks of oxaprozin therapy as well as alternative therapies before initiating therapy with the drug. Use lowest effective dosage and shortest duration of therapy consistent with the patient’s treatment goals.

Symptomatic treatment of osteoarthritis and rheumatoid arthritis.

Management of juvenile rheumatoid arthritis in children 6-16 years of age.