Enbrel and Rozlytrek

• Generic Name: etanercept
• Dosage Forms: subcutaneous injection
• Other Brand Names: Enbrel, Enbrel Prefilled Syringe, Enbrel SureClick, Erelzi Prefilled Syringe, Erelzi Sensoready Pen, Enbrel Mini Prefilled Cartridge

Enbrel (etanercept) is a tumor necrosis factor (TNF) blocker. It works by decreasing TNF, a protein produced by the immune system to helps the body fight infections. In people with autoimmune disorders, the immune system produces too much TNF and mistakenly attacks healthy cells.

Enbrel is used to treat rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis, and to prevent joint damage caused by these conditions.

Enbrel is also used to treat polyarticular juvenile idiopathic arthritis in children who are at least 2 years old.

Enbrel is also used to treat plaque psoriasis in adults and children who are at least 4 years old.

• Generic Name: entrectinib
• Dosage Forms: capsule
• Other Brand Names: Rozlytrek

Rozlytrek (entrectinib) is used in adults to treat non-small cell lung cancer that has spread to other parts of the body (metastatic).

Rozlytrek is also used in adults and children at least 12 years old who have solid tumors that have spread or cannot be safely removed with surgery, or when other treatments have failed or are not safe options.

Rozlytrek is used only if your cancer has a specific abnormal gene. Your doctor will test you for this gene.