Enbrel (Etanercept Prefilled Syringes) and Entyvio Injection

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using vedolizumab together with etanercept may increase the risk of serious infections. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. Contact your doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: The use of tumor necrosis factor (TNF) blockers with other immunosuppressive or myelosuppressive agents may increase the risk of infections. Serious infections and sepsis, including fatalities, have been reported with the use of TNF blockers, particularly in patients on concomitant immunosuppressive therapy. No data are available on the use of TNF blockers specifically with vedolizumab. Concomitant use with other immunosuppressants such as azathioprine or mercaptopurine has been reported to increase the risk of a rare and often fatal cancer of white blood cells known as hepatosplenic T-Cell lymphoma (HSTCL), which has primarily been reported in adolescents and young adults receiving treatment for Crohn's disease or ulcerative colitis. Cases of HSTCL have also occurred during use of these agents alone. Because individuals with rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, or plaque psoriasis may be more likely to develop lymphoma than the general population, it is difficult to assess the added risk of TNF blockers or other immunosuppressants.

MANAGEMENT: The safety and efficacy of vedolizumab in combination with TNF blockers have not been established. Concomitant use should be avoided.

Enbrel (Etanercept Prefilled Syringes)

Generic Name: etanercept

Brand name: Enbrel, Enbrel Prefilled Syringe, Enbrel SureClick, Erelzi Prefilled Syringe, Erelzi Sensoready Pen, Enbrel Mini Prefilled Cartridge

Synonyms: Enbrel

What is Enbrel (Etanercept Prefilled Syringes)?

Entyvio Injection

Generic Name: vedolizumab

Brand name: Entyvio

Synonyms: Vedolizumab

What is Entyvio Injection?