Encorafenib and Fludarabine Intravenous

• Generic Name: encorafenib
• Dosage Forms: n.a.
• Other Brand Names: Braftovi

Encorafenib is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Encorafenib is used in combination with another medicine called binimetinib (Mektovi) to treat melanoma (skin cancer) in people who have a "BRAF" gene mutation. These medicines are for use in treating melanoma that cannot be treated with surgery or has spread to other parts of the body.

Encorafenib may also be used for purposes not listed in this medication guide.

• Generic Name: fludarabine
• Dosage Forms: n.a.
• Other Brand Names: Fludara, Oforta

Fludarabine injection belongs to the group of medicines called antimetabolites. It is used to treat a type of cancer of the white blood cells called B-cell chronic lymphocytic leukemia (CLL). Fludarabine is used in patients with CLL who have already been treated with an alkylating agent (e.g., bendamustine) that did not work well. .

Fludarabine injection interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by fludarabine injection, other effects may also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with fludarabine injection, you and your doctor should talk about the good fludarabine will do as well as the risks of using it.

Fludarabine injection is to be administered only by or under the immediate supervision of your doctor.