Endacof HC and Ruxolitinib Phosphate

• Generic Name: brompheniramine / hydrocodone / pseudoephedrine
• Dosage Forms: n.a.
• Other Brand Names: Bromplex HD, Endacof HC, Visvex, Drocon-CS, Anaplex HD, Bromph HD, BroveX HC, Bromcomp HC, J-Tan D HC, M-END, SymTan A

Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Hydrocodone is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Endacof HC is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

Endacof HC will not treat a cough that is caused by smoking, asthma, or emphysema.

Endacof HC may also be used for purposes not listed in this medication guide.

• Generic Name: ruxolitinib
• Dosage Forms: n.a.
• Other Brand Names: Jakafi

Treatment of intermediate- or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis (designated an orphan drug by FDA for this use).