Entereg and Lazanda

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using alvimopan together with fentaNYL is not recommended. This can cause side effects such as abdominal pain, nausea, vomiting, and diarrhea. The use of alvimopan is discouraged if you have received fentaNYL for more than 7 consecutive days immediately prior to alvimopanadministration. Caution is advised if you have received more than 3 doses of fentaNYL within the week prior to surgery. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: Recent exposure to opioids can increase the sensitivity to mu opioid receptor antagonists.

MANAGEMENT: The use of alvimopan is contraindicated in patients who have received therapeutic doses of opioids for more than 7 consecutive days immediately prior to alvimopan administration. Caution is advised in patients who have received more than 3 doses of an opioid within the week prior to surgery, as these patients were not studied in the postoperative ileus clinical trials. Patients with recent exposure to opioids should be monitored for increased adverse effects such as abdominal pain, nausea and vomiting, and diarrhea.

Entereg

Generic Name: alvimopan

Brand name: Entereg

Synonyms: n.a.

What is Entereg?

Lazanda

Generic Name: fentanyl

Brand name: Lazanda, Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Onsolis, Sublimaze

Synonyms: Lazanda Nasal Spray

What is Lazanda?