Eovist and Rifadin IV

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using rifAMPin together with gadoxetate can interfere with gadoxetate. You should be aware of the possibility of a diagnostic interference if you use both medications. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor

MONITOR: Anionic drugs such as rifamycins may interfere with the hepatic contrast enhancement of gadoxetate by competing for biliary excretion. In animal studies, rifampin blocked the hepatic uptake and decreased the hepatic contrast effect of gadoxetate. The interaction has not been studied in human.

MANAGEMENT: Clinicians should be aware of possible interference with gadoxetate imaging in patients receiving rifamycin therapy.

Eovist

Generic Name: gadoxetate disodium

Brand name: Eovist

Synonyms: n.a.

What is Eovist?

Rifadin IV

Generic Name: rifampin

Brand name: Rifadin IV, Rifadin, Rimactane

Synonyms: n.a.

What is Rifadin IV?