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Epaned and Giapreza

Determining the interaction of Epaned and Giapreza and the possibility of their joint administration.

Check result:
Epaned <> Giapreza
Relevance: 09.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Enalapril may increase the effects of angiotensin II. Blood pressure should be closely monitored during treatment with angiotensin II, and the dosage adjusted as needed.

Professional:

MONITOR: Concomitant use of angiotensin converting enzyme (ACE) inhibitors may increase the pharmacologic response to angiotensin II according to the prescribing information. The mechanism may involve inhibition of ACE that contributes to the metabolism of angiotensin II.

MANAGEMENT: Close monitoring of therapeutic response is recommended when angiotensin II is administered to patients treated with ACE inhibitors.

References
  • "Product Information. Giapreza (angiotensin II)." La Jolla Pharmaceutical, San Diego, CA.
Epaned

Generic Name: enalapril

Brand name: Epaned, Vasotec

Synonyms: n.a.

Giapreza

Generic Name: angiotensin II

Brand name: Giapreza

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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