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Ephedrine and Infumorph

Determining the interaction of Ephedrine and Infumorph and the possibility of their joint administration.

Check result:

Ephedrine <> Infumorph

Relevance: 17.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

One study has suggested that ephedrine may enhance the analgesic effects of morphine. The authors have reported that the addition of ephedrine produced analgesic effects that matched those of approximately double the dose of morphine--without morphine-induced respiratory depression. The clinical consequences of this potentially beneficial interaction have not been studied in large numbers of patients.

References

Tekol Y, Tercan E, Esmaoglu A "Ephedrine enhances analgesic effect of morphine." Acta Anaesthesiol Scand 38 (1994): 396-7

Ephedrine

Generic Name: ephedrine

Brand name: Akovaz

Synonyms: EPHEDrine (Systemic)

What is Ephedrine?

Infumorph

Generic Name: morphine

Brand name: Duramorph PF, Infumorph, Mitigo, Arymo ER, Kadian, MorphaBond ER, Avinza, MS Contin, RMS, Roxanol

Synonyms: Infumorph (injection)

What is Infumorph?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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