Epirubicin Intravenous, Injection and Melphalan Tablets
Determining the interaction of Epirubicin Intravenous, Injection and Melphalan Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited anecdotal data suggest an increased risk of doxorubicin-induced cardiomyopathy in patients who have previously received melphalan. The mechanism of this suspected interaction is unknown. Although conclusive proof that melphalan sensitizes the myocardium is lacking, anthracyclines should be administered cautiously to patients who have had extensive melphalan therapy.
- Bitran JD "Doxorubicin cardiotoxicity and melphalan" Ann Intern Med 95 (1981): 243-4
Generic Name: epirubicin
Brand name: Ellence, Pharmorubicin Pfs, Pharmorubicin RDF
Synonyms: Epirubicin, EPIrubicin
Generic Name: melphalan
Brand name: Alkeran, Alkeran IV, Evomela
Synonyms: Melphalan (oral/injection), Melphalan
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Epirubicin Intravenous, Injection-Memantine
- Epirubicin Intravenous, Injection-Memantine and Donepezil
- Epirubicin Intravenous, Injection-Memantine and Donepezil Capsules
- Epirubicin Intravenous, Injection-Memantine ER capsules
- Epirubicin Intravenous, Injection-Memantine ER Tablets
- Epirubicin Intravenous, Injection-Memantine Extended-Release Capsules
- Melphalan Tablets-EPIsnap
- Melphalan Tablets-Epitol
- Melphalan Tablets-Epivir
- Melphalan Tablets-Epivir (Lamivudine Oral Solution)
- Melphalan Tablets-Epivir (Lamivudine Tablets)
- Melphalan Tablets-Epivir A/F