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Epoprostenol Sodium and Medi-Tussin Cough/Cold

Determining the interaction of Epoprostenol Sodium and Medi-Tussin Cough/Cold and the possibility of their joint administration.

Check result:

Epoprostenol Sodium <> Medi-Tussin Cough/Cold

Relevance: 06.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using pseudoephedrine together with epoprostenol. Using these medications together can make epoprostenol less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.

MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.

References

Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
"Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
"Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.

Epoprostenol Sodium

Generic Name: epoprostenol

Brand name: Flolan, Veletri

Synonyms: Epoprostenol

What is Epoprostenol Sodium?

Medi-Tussin Cough/Cold

Generic Name: dextromethorphan / guaifenesin / pseudoephedrine

Brand name: Altarussin CF, Capmist DM, Despec DM, Entre-Cough, Maxifed DMX, Robitussin Cold and Cough, Tusnel, Medi-Tussin Cough/Cold, Tussin Cold/Congestion, Poly-Vent DM, Tusnel-DM Pediatric Drops

Synonyms: Dextromethorphan, guaifenesin, and pseudoephedrine, Guaifenesin, Pseudoephedrine, and Dextromethorphan

What is Medi-Tussin Cough/Cold?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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