Epoprostenol Sodium and Promethazine and Phenylephrine
Determining the interaction of Epoprostenol Sodium and Promethazine and Phenylephrine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using phenylephrine together with epoprostenol. Using these medications together can make epoprostenol less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.
MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.
- Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
- "Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
- "Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: epoprostenol
Brand name: Flolan, Veletri
Synonyms: Epoprostenol
Generic Name: phenylephrine / promethazine
Brand name: Phenergan VC, Promethazine VC Plain, Promethazine VC
Synonyms: Phenylephrine and promethazine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Epoprostenol Sodium-Promethazine Hydrochloride
- Epoprostenol Sodium-Promethazine injection
- Epoprostenol Sodium-Promethazine Injection, Intravenous
- Epoprostenol Sodium-Promethazine rectal
- Epoprostenol Sodium-Promethazine Suppositories
- Epoprostenol Sodium-Promethazine Syrup
- Promethazine and Phenylephrine-Eposin
- Promethazine and Phenylephrine-Eprosartan
- Promethazine and Phenylephrine-Eprosartan and Hydrochlorothiazide
- Promethazine and Phenylephrine-Eprosartan Mesylate
- Promethazine and Phenylephrine-Epsal
- Promethazine and Phenylephrine-Epsom Salt