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Eptifibatide Injection and Jantoven

Determining the interaction of Eptifibatide Injection and Jantoven and the possibility of their joint administration.

Check result:
Eptifibatide Injection <> Jantoven
Relevance: 03.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using warfarin together with eptifibatide this can cause you to bleed more easily. You may need a dose adjustment in addition to testing of your prothrombin time or International Normalized Ratio (INR). Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The risk of bleeding, including major bleeding (intracranial hemorrhage or a decrease in hemoglobin greater than 5 mg/dl) is significantly more likely when oral anticoagulants and glycoprotein IIb/IIIa inhibitors are given together.

MANAGEMENT: Some manufacturers of GP IIb/IIIa inhibitors consider their use contraindicated if patients have received oral anticoagulants within 7 days unless the prothrombin time is less than or equal to 1.2 times control. Bleeding precautions should be observed and patients should be closely monitored for clinical and laboratory evidence of adverse effects.

References
  • "Product Information. ReoPro (abciximab)." Lilly, Eli and Company, Indianapolis, IN.
  • "Product Information. Integrilin (eptifibatide)." Schering Laboratories, Kenilworth, NJ.
Eptifibatide Injection

Generic Name: eptifibatide

Brand name: Integrilin

Synonyms: Eptifibatide

Jantoven

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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