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EQL Daytime Cold/Flu Relief and Lanoxin (Digoxin Injection)

Determining the interaction of EQL Daytime Cold/Flu Relief and Lanoxin (Digoxin Injection) and the possibility of their joint administration.

Check result:
EQL Daytime Cold/Flu Relief <> Lanoxin (Digoxin Injection)
Relevance: 05.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using digoxin together with pseudoephedrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using pseudoephedrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.

MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.

References
  • "Product Information. Claritin-D (loratadine-pseudoephedrine)." Schering-Plough, Liberty Corner, NJ.
  • "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
  • "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
  • "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
EQL Daytime Cold/Flu Relief

Generic Name: acetaminophen / dextromethorphan / pseudoephedrine

Brand name: Alka-Seltzer Plus Flu/Body, DayQuil Multi-Symptom Cold/Flu, EQ Daytime Cold/Flu Relief, EQ Flu Relief, EQL Daytime Cold/Flu Relief, Tylenol Flu Maximum Strength, Sudafed Severe Cold, Tylenol Cold and Flu No Drowsiness Powder, Tylenol Cold No Drowsiness, Theraflu No Drowsiness Maximum Strength, Triaminic Sore Throat Formula, Contac Severe Cold and Flu Non Drowsy, Tylenol Cough Liquid with Decongestant, DayQuil, Day Time Multi Symptom, Triaminic Cold and Fever Formula, Sudafed Decongestant Cold and Cough, Tylenol Cold Severe Congestion, Tylenol Infants Cold Plus Cough, Robitussin Honey Flu, Extra Strength Tylenol Flu Daytime, Non-Drowsy Super Strength Contac Complete, Contact Cold and Sore Throat, Tylenol Cold & Flu Severe Day Time, Vicks Dayquil Daytime Cold/Flu, Triaminic Cough & Sore Throat, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Softchews Cough & Sore Throat, Day Relief Cold and Flu, Tylenol Cold & Flu Daytime, Tylenol Cold Non-Drowsy Caplets, Tylenol Cold Non-Drowsy Gelcaps, Daytime Cold and Flu Relief, Daytime Non-Drowsy, Theraflu Daytime Severe Cold, Severe Cold Multi-Sympton

Synonyms: n.a.

Lanoxin (Digoxin Injection)

Generic Name: digoxin

Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin

Synonyms: Lanoxin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.