Equaline Acid Reducer and Lazanda
Determining the interaction of Equaline Acid Reducer and Lazanda and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Cimetidine may increase the blood levels and effects of fentaNYL. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience dizziness, fainting, confusion, excessive drowsiness, slow heart rate, shallow or difficult breathing, and/or shortness of breath. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Cimetidine may increase the action of narcotic analgesics. Cases of respiratory depression and apnea have been reported. The mechanism is unknown.
MANAGEMENT: Patients' vital signs should be closely monitored while receiving this combination. If clinically significant respiratory depression occurs, the drugs should be withdrawn. The use of a narcotic antagonist, such as naloxone, may be needed.
- Lam AM "Potentially lethal interaction of cimetidine and morphine." Can Med Assoc J 125 (1981): 820
- Fine A, Churchill DN "Potentially lethal interaction of cimetidine and morphine." Can Med Assoc J 124 (1981): 1434, 1436
- Lam AM, Clement JL "Effect of cimetidine premedication on morphine-induced ventilatory depression." Can Anaesth Soc J 31 (1984): 36-43
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: n.a.
Generic Name: fentanyl
Brand name: Lazanda, Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Onsolis, Sublimaze
Synonyms: Lazanda Nasal Spray
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a 
Equaline Acid Reducer - Laz-a