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Equaline Acid Reducer and Zolate

Determining the interaction of Equaline Acid Reducer and Zolate and the possibility of their joint administration.

Check result:

Equaline Acid Reducer <> Zolate

Relevance: 06.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Cimetidine may interfere with the metabolism of vitamin D to its biologically active form. The proposed mechanism is inhibition of hepatic hydroxylation. The clinical significance is unknown. It may be advisable to consider Vitamin D supplementation.

References

Odes HS, Fraser GM, Krugliak P, et al "Effect of cimetidine on hepatic vitamin D metabolism in humans." Digestion 46 (1990): 61-4
"Product Information. Fosamax Plus D (alendronate-cholecalciferol)." Merck & Company Inc, West Point, PA.

Equaline Acid Reducer

Generic Name: cimetidine

Brand name: Tagamet HB, Tagamet

Synonyms: n.a.

What is Equaline Acid Reducer?

Zolate

Generic Name: cholecalciferol / folic acid

Brand name: Ortho D, Zolate, Ortho DF, Genicin Vita-D

Synonyms: n.a.

What is Zolate?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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