Erdafitinib and Lortab (Hydrocodone and Acetaminophen Liquid)
Determining the interaction of Erdafitinib and Lortab (Hydrocodone and Acetaminophen Liquid) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with erdafitinib may alter the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme, resulting in increased toxicity or decreased efficacy of these drugs. In vitro, erdafitinib has been shown to be a time-dependent inhibitor as well as inducer of CYP450 3A4. However, no pharmacokinetic data are available from drug interaction studies. MANAGEMENT: Concomitant use of erdafitinib and sensitive CYP450 3A4 substrates or substrates with narrow therapeutic ranges should generally be avoided. References "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Professional:GENERALLY AVOID: Coadministration with erdafitinib may alter the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme, resulting in increased toxicity or decreased efficacy of these drugs. In vitro, erdafitinib has been shown to be a time-dependent inhibitor as well as inducer of CYP450 3A4. However, no pharmacokinetic data are available from drug interaction studies.
MANAGEMENT: Concomitant use of erdafitinib and sensitive CYP450 3A4 substrates or substrates with narrow therapeutic ranges should generally be avoided.
- "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Generic Name: acetaminophen / hydrocodone
Brand name: Hycet, Lorcet, Lortab 10/325, Lortab 5/325, Lortab 75/325, Lortab Elixir, Norco, Verdrocet, Vicodin, Xodol, Zamicet, Anexsia, Dolorex Forte, Liquicet, Lortab, Maxidone, Polygesic, Stagesic, Zydone, Zyfrel
Synonyms: Lortab
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Erdafitinib-Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)
- Erdafitinib-Lortab Oral Solution
- Erdafitinib-Lortab Tablets
- Erdafitinib-Lortuss DM
- Erdafitinib-Lortuss EX
- Erdafitinib-Lortuss LQ
- Lortab (Hydrocodone and Acetaminophen Liquid)-Erelzi Prefilled Syringe
- Lortab (Hydrocodone and Acetaminophen Liquid)-Erelzi Sensoready Pen
- Lortab (Hydrocodone and Acetaminophen Liquid)-Erelzi Subcutaneous
- Lortab (Hydrocodone and Acetaminophen Liquid)-Ergocalciferol
- Lortab (Hydrocodone and Acetaminophen Liquid)-Ergocalciferol Capsules and Tablets
- Lortab (Hydrocodone and Acetaminophen Liquid)-Ergocalciferol Solution