Erdafitinib and Sunmark Anti-Diarrheal
Determining the interaction of Erdafitinib and Sunmark Anti-Diarrheal and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with erdafitinib may increase the plasma concentrations of drugs that are substrates of the P-glycoprotein (P-gp) efflux transporter, resulting in increased toxicity of these drugs. In vitro, erdafitinib has been shown to be an inhibitor of P-gp. However, no pharmacokinetic data are available from drug interaction studies. MANAGEMENT: Concomitant use of erdafitinib and P-gp substrates should generally be avoided. If concomitant use is required, administer erdafitinib at least 6 hours before or after administration of P-gp substrates with narrow therapeutic ranges. References "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Professional:GENERALLY AVOID: Coadministration with erdafitinib may increase the plasma concentrations of drugs that are substrates of the P-glycoprotein (P-gp) efflux transporter, resulting in increased toxicity of these drugs. In vitro, erdafitinib has been shown to be an inhibitor of P-gp. However, no pharmacokinetic data are available from drug interaction studies.
MANAGEMENT: Concomitant use of erdafitinib and P-gp substrates should generally be avoided. If concomitant use is required, administer erdafitinib at least 6 hours before or after administration of P-gp substrates with narrow therapeutic ranges.
- "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Generic Name: loperamide
Brand name: Diamode, Imodium A-D, Imodium A-D EZ Chews, Imodium A-D New Formula, Imodium, Maalox Anti-Diarrheal, Pepto Diarrhea Control, Imotil, Kao-Paverin, Kaopectate 1-D, Diar-Aid, Anti-Diarrheal [OTC]
Synonyms: Good Neighbor Anti-Diarrheal
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Erdafitinib-Sunmark Anti-Diarrheal Tablet
- Erdafitinib-SunMark ClearLax
- Erdafitinib-Sunmark Hour Allergy Relief
- Erdafitinib-Sunmark Ibuprofen Cold and Sinus
- Erdafitinib-Sunmark Loratadine
- Erdafitinib-Sunmark Miconazole 7
- Sunmark Anti-Diarrheal-Erelzi Prefilled Syringe
- Sunmark Anti-Diarrheal-Erelzi Sensoready Pen
- Sunmark Anti-Diarrheal-Erelzi Subcutaneous
- Sunmark Anti-Diarrheal-Ergocalciferol
- Sunmark Anti-Diarrheal-Ergocalciferol Capsules and Tablets
- Sunmark Anti-Diarrheal-Ergocalciferol Solution