Erdafitinib and Zohydro ER Capsules
Determining the interaction of Erdafitinib and Zohydro ER Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with erdafitinib may alter the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme, resulting in increased toxicity or decreased efficacy of these drugs. In vitro, erdafitinib has been shown to be a time-dependent inhibitor as well as inducer of CYP450 3A4. However, no pharmacokinetic data are available from drug interaction studies. MANAGEMENT: Concomitant use of erdafitinib and sensitive CYP450 3A4 substrates or substrates with narrow therapeutic ranges should generally be avoided. References "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Professional:GENERALLY AVOID: Coadministration with erdafitinib may alter the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme, resulting in increased toxicity or decreased efficacy of these drugs. In vitro, erdafitinib has been shown to be a time-dependent inhibitor as well as inducer of CYP450 3A4. However, no pharmacokinetic data are available from drug interaction studies.
MANAGEMENT: Concomitant use of erdafitinib and sensitive CYP450 3A4 substrates or substrates with narrow therapeutic ranges should generally be avoided.
- "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Generic Name: hydrocodone
Brand name: Hysingla ER, Zohydro ER, Vantrela ER
Synonyms: Hydrocodone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Erdafitinib-Zoladex
- Erdafitinib-Zoladex (Goserelin Implant 10.8 mg)
- Erdafitinib-Zoladex (Goserelin Implant 3.6 mg)
- Erdafitinib-Zoladex 3-Month
- Erdafitinib-Zoladex Implant
- Erdafitinib-Zolate
- Zohydro ER Capsules-Erelzi Prefilled Syringe
- Zohydro ER Capsules-Erelzi Sensoready Pen
- Zohydro ER Capsules-Erelzi Subcutaneous
- Zohydro ER Capsules-Ergocalciferol
- Zohydro ER Capsules-Ergocalciferol Capsules and Tablets
- Zohydro ER Capsules-Ergocalciferol Solution