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Erelzi Prefilled Syringe and Talimogene laherparepvec Injection

Determining the interaction of Erelzi Prefilled Syringe and Talimogene laherparepvec Injection and the possibility of their joint administration.

Check result:
Erelzi Prefilled Syringe <> Talimogene laherparepvec Injection
Relevance: 28.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

If you are currently being treated or have recently been treated with etanercept, you should let your doctor know before receiving talimogene laherparepvec. Depending on the dose and length of time you have been on etanercept, you may be at risk for developing a potentially life-threatening herpes infection from exposure to talimogene laherparepvec. In some situations, your doctor may want to delay treatment with talimogene laherparepvec to give your body time to recover from the effects of etanercept therapy. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Talimogene laherparepvec is a live, attenuated herpes simplex virus. Administration during immunosuppressant or intense antineoplastic therapy may be associated with a risk of potentially life-threatening disseminated herpetic infection due to enhanced virus replication in the presence of diminished immune competence. Patients may be immunosuppressed if they have recently received or are receiving alkylating agents, antimetabolites, radiation, some antirheumatic agents, high dosages of corticosteroids or adrenocorticotropic agents, or long-term topical or inhaled corticosteroids.

MANAGEMENT: Talimogene laherparepvec should not be used in patients receiving immunosuppressive therapy or cancer chemotherapy. Treatment with talimogene laherparepvec may need to be deferred until after such therapy is discontinued and the patient's immune system has sufficiently recovered.

References
  • "Product Information. Imlygic (talimogene laherparepvec)." Amgen USA, Thousand Oaks, CA.
Erelzi Prefilled Syringe

Generic Name: etanercept

Brand name: Enbrel, Erelzi Prefilled Syringe, Erelzi Sensoready Pen, Enbrel Prefilled Syringe, Enbrel SureClick, Enbrel Mini Prefilled Cartridge

Synonyms: n.a.

Talimogene laherparepvec Injection

Generic Name: talimogene laherparepvec

Brand name: Imlygic

Synonyms: Talimogene laherparepvec, Talimogene Laherparepvec

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.