Ergotamine and Caffeine and Ivacaftor and lumacaftor

• Generic Name: caffeine / ergotamine
• Dosage Forms: tablet, film coated
• Other Brand Names: Cafergot, Migergot, Wigraine, Cafetrate, Ercaf, Cafatine

Caffeine is a stimulant that causes narrowing of blood vessels (vasoconstriction).

Ergotamine is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). It works by narrowing the blood vessels around the brain. Ergotamine also affects blood flow patterns that are associated with certain types of headaches.

Caffeine and ergotamine is a combination medicine used to treat or prevent a migraine type headache.

This medication will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks.

Caffeine and ergotamine should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.

Caffeine and ergotamine may also be used for purposes not listed in this medication guide.

• Generic Name: ivacaftor / lumacaftor
• Dosage Forms: n.a.
• Other Brand Names: Orkambi

Ivacaftor and lumacaftor is used to treat cystic fibrosis in adults and children who are at least 2 years old.

Ivacaftor and lumacaftor is for use only in patients with a specific gene mutation related to cystic fibrosis. Before you take ivacaftor and lumacaftor, you may need a medical test to make sure you have this gene mutation.

Ivacaftor and lumacaftor may also be used for purposes not listed in this medication guide.