Ergotamine Tartrate and Mitigare

• Generic Name: ergotamine
• Dosage Forms: n.a.
• Other Brand Names: Ergomar

Prevention or abortion of vascular headaches (e.g., migraine, cluster headaches), when used alone or in fixed combination with caffeine. Should not be used for chronic daily management of vascular headaches.

Generally not preferred for terminating acute cluster headaches; onset of action is slower than that of other therapies (e.g., sumatriptan, oxygen).

Has been used for short-term (e.g., up to 3 weeks) prophylaxis of episodic cluster headaches to suppress a series of attacks and reduce duration of cluster period. Prophylactic administration at bedtime may be particularly useful in selected patients with nocturnal cluster attacks.

Ineffective in the treatment of muscle contraction headaches.

• Generic Name: colchicine
• Dosage Forms: capsule
• Other Brand Names: Colcrys, Mitigare

Mitigare affects the way the body responds to uric acid crystals, which reduces swelling and pain.

Because Mitigare was developed prior to federal regulations requiring FDA review of all marketed drug products, not all uses for this medicine have been approved by the FDA.

The Colcrys brand of colchicine is FDA-approved to treat or prevent gout in adults, and to treat a genetic condition called Familial Mediterranean Fever in adults and children who are at least 4 years old.

The Mitigare brand of colchicine is FDA-approved to prevent gout flares in adults.

Generic forms of colchicine have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (such as swelling, redness, warmth, and pain).

Mitigare is not a cure for gouty arthritis or Behcets syndrome, and it will not prevent these diseases from progressing. This medicine should not be used as a routine pain medication for other conditions.

Mitigare may also be used for purposes not listed in this medication guide.