Eribulin Mesylate and Eslicarbazepine Acetate

• Generic Name: eribulin
• Dosage Forms: n.a.
• Other Brand Names: Halaven

Treatment of metastatic breast cancer in patients who have previously received at least 2 chemotherapeutic regimens, including an anthracycline and a taxane, in either the adjuvant or metastatic setting.

There is no generally accepted standard of care for management of advanced and heavily pretreated anthracycline- and taxane-refractory metastatic breast cancer. Some clinicians recommend individualizing therapy based on factors such as patient’s disease stage and tumor type, performance status, quality of life, preferences, treatment history (e.g., toxicity), underlying medical conditions, and expected benefits and risks of each option.

• Generic Name: eslicarbazepine
• Dosage Forms: n.a.
• Other Brand Names: Aptiom

Management (in combination with other anticonvulsants) of partial-onset seizures in adults.

In longer-term extension studies, reductions in seizure frequency were maintained for at least 1 year.

Controlled comparative trials between eslicarbazepine acetate and oxcarbazepine needed to fully evaluate the relative efficacy and tolerability of these structurally related anticonvulsants (see Actions).

Once-daily dosage regimen may help improve patient compliance.