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Ertugliflozin and Novolin 70/30 (Insulin NPH and Insulin Regular (Vials))

Determining the interaction of Ertugliflozin and Novolin 70/30 (Insulin NPH and Insulin Regular (Vials)) and the possibility of their joint administration.

Check result:
Ertugliflozin <> Novolin 70/30 (Insulin NPH and Insulin Regular (Vials))
Relevance: 05.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ertugliflozin may help control blood glucose levels, which may lead to a reduction in your dosage requirement of insulin regular or any other diabetic medications you are receiving. Your blood glucose should be closely monitored so that medications may be adjusted accordingly by your doctor. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Likewise, if ertugliflozin is discontinued, your blood glucose may increase and hyperglycemia may occur, which may require readjustment of your medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSE: Coadministration of a sodium-glucose co-transporter 2 (SGLT-2) inhibitor with an insulin secretagogue (e.g., sulfonylurea, meglitinide) or insulin may potentiate the risk of hypoglycemia.

MANAGEMENT: A lower dosage of the insulin secretagogue or insulin may be required when used in combination with an SGLT-2 inhibitor.

References
  • "Product Information. Jardiance (empagliflozin)." Boehringer Ingelheim, Ridgefield, CT.
  • "Product Information. Steglatro (ertugliflozin)." Merck & Company Inc, Whitehouse Station, NJ.
  • "Product Information. Invokana (canagliflozin)." Janssen Pharmaceuticals, Titusville, NJ.
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Farxiga (dapagliflozin)." Bristol-Myers Squibb, Princeton, NJ.
Ertugliflozin

Generic Name: ertugliflozin

Brand name: Steglatro

Synonyms: n.a.

Novolin 70/30 (Insulin NPH and Insulin Regular (Vials))

Generic Name: insulin isophane / insulin regular

Brand name: Humulin 70/30, HumuLIN 70/30 KwikPen, Novolin 70/30, ReliOn/Novolin 70/30, Humulin 50/50, Insulin Pork Mix, HumuLIN 70/30 Pen, NovoLIN 70/30 Innolet, NovoLIN 70/30 PenFill, Relion NovoLIN 70/30 Innolet, NovoLIN 70/30 FlexPen, ReliOn/NovLIN 70/30 FlexPen, Humulin 50/50, Novolin 70/30

Synonyms: Insulin isophane and insulin regular, Insulin NPH and Insulin Regular

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.