EryPed and Zafirlukast

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using erythromycin together with zafirlukast may decrease the effects of zafirlukast. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Erythromycin may decrease zafirlukast plasma concentrations. In one study (n=11) concomitant erythromycin 500 mg 3 times daily reduced zafirlukast levels by 40%. The mechanism and clinical significance are unknown. Reduced efficacy may result.

MANAGEMENT: The clinician should be aware of this interaction and observation for decreased zafirlukast efficacy is recommended if the combination is used.

EryPed

Generic Name: erythromycin

Brand name: E. E. S, EryPed, EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV

Synonyms: n.a.

What is EryPed?

Zafirlukast

Generic Name: zafirlukast

Brand name: Accolate

Synonyms: n.a.

What is Zafirlukast?