Erythromycin and sulfisoxazole and Loratadine Tablet
Determining the interaction of Erythromycin and sulfisoxazole and Loratadine Tablet and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Macrolide antibiotics may increase the plasma concentrations of loratadine through inhibition of CYP450 3A4 or 2D6 enzymes. Loratadine levels may increase by 40% when coadministered with erythromycin. Clinical monitoring of patient response and tolerance is recommended when macrolides are administered with non-sedating antihistamines. Azithromycin and dirithromycin are not expected to affect loratadine levels and may be considered as alternatives.
- "Product Information. Claritin (loratadine)." Schering Laboratories, Kenilworth, NJ.
- Nahata M "Drug interactions with azithromycin and the macrolides: an overview." J Antimicrob Chemother 37 ( Suppl (1996): 133-42
- Ament PW, Paterson A "Drug interactions with the nonsedating antihistamines." Am Fam Physician 56 (1997): 223
Generic Name: erythromycin / sulfisoxazole
Brand name:
Synonyms: Erythromycin and sulfisoxazole (Oral), Erythromycin and Sulfisoxazole
Generic Name: loratadine
Brand name: Alavert, Claritin, Claritin Reditab, Clear-Atadine, Dimetapp ND, Ohm Allergy Relief, QlearQuil All Day & Night, Tavist ND, Wal-itin
Synonyms: Loratadine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Erythromycin and sulfisoxazole-Loratadine-D 12 Hour
- Erythromycin and sulfisoxazole-Loratadine-D 24 Hour
- Erythromycin and sulfisoxazole-Lorazepam
- Erythromycin and sulfisoxazole-Lorazepam Concentrate
- Erythromycin and sulfisoxazole-Lorazepam injection
- Erythromycin and sulfisoxazole-Lorazepam Injection Solution
- Loratadine Tablet-Erythromycin Base Filmtab
- Loratadine Tablet-Erythromycin Capsules
- Loratadine Tablet-Erythromycin Delayed-Release Tablet
- Loratadine Tablet-Erythromycin Delayed-Release Tablets and Capsules
- Loratadine Tablet-Erythromycin Ethyl Succinate Tablets
- Loratadine Tablet-Erythromycin Filmtabs