About us Contacts Drug interactions: 390 212
Drug search by name

Esketamine and Nasal Mist

Determining the interaction of Esketamine and Nasal Mist and the possibility of their joint administration.

Check result:
Esketamine <> Nasal Mist
Relevance: 26.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

It is not known how esketamine and oxymetazoline nasal may affect each other when they are used at the same time. If you need to use oxymetazoline nasal on a day when dosing of esketamine is scheduled, you should use it at least one hour before esketamine. Talk to your doctor or pharmacist if you have questions on how to take these or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Data are limited with respect to any potential interaction between intranasal esketamine and other nasal products during concomitant administration. In pharmacokinetic studies, mometasone furoate and oxymetazoline hydrochloride administered intranasally one hour before esketamine demonstrated no clinically significant effects on esketamine peak plasma concentration and exposure.

MANAGEMENT: To minimize the risk of interaction, patients who require a nasal corticosteroid or nasal decongestant on a day when esketamine dosing is scheduled should administer these medications at least one hour before esketamine.

References
  • "Product Information. Spravato (esketamine)." Janssen Pharmaceuticals, Titusville, NJ.
Esketamine

Generic Name: esketamine

Brand name: Spravato

Synonyms: Esketamine (nasal)

Nasal Mist

Generic Name: oxymetazoline nasal

Brand name: 12 Hour Nasal, Afrin, Afrin No Drip Sinus, Allerest 12 Hour Nasal Spray, Dristan 12-Hour, Duramist Plus, Duration, Mucinex Full Force, Mucinex Moisture Smart, Nasal Mist, Neo-Synephrine 12 Hour, Nostrilla, NRS Nasal, Sinarest Nasal, Sinex Long-Acting, Sudafed OM Sinus Cold, Zicam Extreme Congestion Relief, Zicam Sinus Relief, Afrin Menthol Spray, Afrin Nasal Spray, Afrin NoDrip Extra Moisture, Afrin NoDrip Original, Afrin NoDrip Sinus, Afrin Sinus, Dristan Spray, Long Lasting Nasal Spray, Mucinex Nasal Spray Full Force, Mucinex Nasal Spray Moisture, Mucinex Sinus-Max Clear & Cool, Nasal Decongestant Spray, Nasal Spray 12 Hour, Nasal Spray Max Strength, Neo-Synephrine 12 Hour Spray, NRS Nasal Relief, QlearQuil, Sinus Nasal Spray, Vicks Sinex 12 Hour Decongest, Vicks Sinex Moisturizing, Vicks Sinex Severe Decongest, Vicks Sinex

Synonyms: Oxymetazoline nasal, Oxymetazoline (Nasal)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction