Esketamine Hydrochloride and Pamprin Cramp Formula

• Generic Name: esketamine
• Dosage Forms: n.a.
• Other Brand Names: Spravato

Used intranasally for treatment (in combination with an oral antidepressant) of treatment-resistant depression. Although there are various definitions of treatment-resistant depression, the condition is often defined as the failure of ≥2 trials of first-line antidepressants given in an adequate dosage for an adequate duration of therapy.

Intranasal esketamine substantially improved depressive symptoms as measured by the Montgomery-Asberg Depression Rating Scale (MADRS) within 24 hours of administration in a short-term clinical trial and prolonged time to relapse in a longer-term maintenance trial.

Esketamine is the S-enantiomer of racemic ketamine, which is an anesthetic agent. However, esketamine is not labeled for use as an anesthetic agent; efficacy and safety not established.

• Generic Name: acetaminophen / magnesium salicylate / pamabrom
• Dosage Forms: n.a.
• Other Brand Names: Pamprin Cramp Formula

Acetaminophen is a pain reliever and fever reducer.

Magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). Pamprin Cramp Formula works by reducing substances in the body that cause pain, fever, and inflammation.

Pamabrom is a diuretic (water pill).

Pamprin Cramp Formula is a combination medicine used to treat menstrual symptoms such as cramps, headache, backache, muscle aches, bloating, and fluid retention.

Pamprin Cramp Formula may also be used for other purposes not listed in this medication guide.