Eslicarbazepine Acetate and Phentermine Hydrochloride

• Generic Name: eslicarbazepine
• Dosage Forms: n.a.
• Other Brand Names: Aptiom

Management (in combination with other anticonvulsants) of partial-onset seizures in adults.

In longer-term extension studies, reductions in seizure frequency were maintained for at least 1 year.

Controlled comparative trials between eslicarbazepine acetate and oxcarbazepine needed to fully evaluate the relative efficacy and tolerability of these structurally related anticonvulsants (see Actions).

Once-daily dosage regimen may help improve patient compliance.

• Generic Name: phentermine
• Dosage Forms: n.a.
• Other Brand Names: Adipex-P, Lomaira, Suprenza

Adjunct to exercise, behavioral modification, and caloric restriction in the short-term management (a few weeks) of exogenous obesity.

May use in patients with no underlying risk factor but a pretreatment body mass index (BMI) of ≥30 kg/m2 and in those with an underlying risk factor (e.g., hypertension, diabetes mellitus, hyperlipidemia) and a pretreatment BMI of ≥27 kg/m2.

Use only for short-term monotherapy; not for use in combination with any other drug for weight loss, including SSRI antidepressants (e.g., fluoxetine, fluvoxamine, paroxetine, sertraline) or MAO inhibitors. (See Warnings under Cautions.)