Esmolol Hydrochloride and Methoxyflurane
Determining the interaction of Esmolol Hydrochloride and Methoxyflurane and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:If you are currently using esmolol, let your doctor know before you undergo anesthesia with methoxyflurane. Combining these medications may occasionally cause a profound decrease in blood pressure. You will need to be closely monitored during anesthesia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The antihypertensive effects of methoxyflurane and beta blockers may be additive. The combination may cause profound hypotension. Older anesthetics such as methoxyflurane have more severe circulatory depressant effects in the presence of beta-blockade.
MANAGEMENT: It is currently recommended that beta blocker therapy not be routinely withdrawn prior to surgery. However, in general, patients taking beta blockers should not be anaesthetized with methoxyflurane. Instead, an anesthetic with minimal negative inotropic activity may be considered. If methoxyflurane must be used, beta blocker therapy should be withdrawn gradually and generally completed 24 to 48 hours before anesthesia.
- "Product Information. Lopressor (metoprolol)." Novartis Pharmaceuticals, East Hanover, NJ.
- Hunter JM "Synergism between halothane and labetalol." Anaesthesia 34 (1979): 257-9
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Scott DB, Buckley FP, Littlewood DG, Macrae WR, Arthur GR, Drummond GB "Circulatory effects of labetalol during halothane anaesthesia." Anaesthesia 33 (1978): 145-56
Generic Name: esmolol
Brand name: Brevibloc
Synonyms: Esmolol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Esmolol Hydrochloride-Methscopolamine
- Esmolol Hydrochloride-Methscopolamine Bromide
- Esmolol Hydrochloride-Methsuximide
- Esmolol Hydrochloride-Methyclothiazide
- Esmolol Hydrochloride-Methyl Aminolevulinate
- Esmolol Hydrochloride-Methyl aminolevulinate topical
- Methoxyflurane-Esmolol Injection
- Methoxyflurane-Esmolol Intravenous
- Methoxyflurane-Esomep-EZS
- Methoxyflurane-Esomeprazole
- Methoxyflurane-Esomeprazole and naproxen
- Methoxyflurane-Esomeprazole Capsules