Esomeprazole Sodium and Incobotulinumtoxina Intramuscular

• Generic Name: esomeprazole
• Dosage Forms: n.a.
• Other Brand Names: Esomeprazole Strontium, Nexium, Nexium, NexIUM 24HR, Nexium IV

Short-term treatment of symptomatic GERD (e.g., heartburn) in patients without erosive esophagitis.

Short-term treatment of erosive esophagitis (diagnostically confirmed) in patients with GERD. Short-term treatment of erosive esophagitis due to acid-mediated GERD in infants.

Maintain healing, symptom resolution, and decrease recurrence of erosive esophagitis.

IV as short-term alternative to oral therapy in patients with erosive esophagitis who are unable to take the drug orally; safety and efficacy not established beyond 10 days.

Treatment of Helicobacter pylori infection and duodenal ulcer disease (active duodenal ulcer or history of duodenal ulcer in the past 5 years). Used in conjunction with amoxicillin and clarithromycin (triple therapy).

Reduction in the occurrence of gastric ulcers associated with chronic NSAIA therapy in patients at risk (i.e., ≥60 years of age and/or history of gastric ulcer). Effect on occurrence of duodenal ulcers not established.

Some evidence for use of proton-pump inhibitors (e.g., omeprazole) for gastric acid suppressive therapy as an adjunct in the management of upper GI Crohn’s disease, including esophageal, gastroduodenal, and jejunoileal disease.

• Generic Name: incobotulinumtoxinA
• Dosage Forms: n.a.
• Other Brand Names: Xeomin

IncobotulinumtoxinA is used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck). It is also used to treat upper limb spasticity (muscle spasms in the upper arms). Incobotulinumtoxina is also used to treat a certain eye condition called blepharospasm (a condition where the eyelid will not stay open because of a muscle spasm) in patients who have already been treated with onabotulinumtoxinA (Botox®). It is also used to treat long-lasting sialorrhea (excessive drooling). IncobotulinumtoxinA is also used cosmetically to improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines).

IncobotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.

Incobotulinumtoxina is available only with your doctor's prescription and will be given by your doctor.