Estra Pellets and Nutropin AQ NuSpin 10

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Estradiol may decrease the effects of somatropin. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration of oral estrogen replacement therapy may diminish the therapeutic effects of somatropin. The mechanism of this interaction has not been delineated; however, it is known that orally administered estrogen suppresses growth hormone (GH) dependent IGF-1 (insulin-like growth factor/somatomedin-C) production in the liver. Gender differences have been shown in responsiveness to GH with women requiring higher doses than men to achieve a similar response. The results of a study demonstrated that women taking oral estrogen required higher doses of GH to achieve an adequate response compared with men or women using transdermal estrogen. In addition, the study showed that GH requirements were also higher for GH-deficient women receiving primarily oral estrogen replacement therapy than for eugonadal GH-deficient women. This interaction does not appear to apply to non-orally administered estrogens, such as transdermal administration.

MANAGEMENT: Patients receiving somatropin with oral estrogen replacement therapy should be monitored for diminished GH efficacy. A higher dose of somatropin may be required to maintain the serum IGF-1 levels within the normal age-appropriate range in order to achieve the defined treatment goal. Dosage adjustments as well as clinical and laboratory monitoring should be considered whenever oral estrogen replacement therapy is added to or withdrawn from therapy with somatropin.

Estra Pellets

Generic Name: estradiol

Brand name: Alora, Climara, Estradiol Patch, Menostar, Minivelle, Vivelle-Dot, Estraderm, Vivelle, Delestrogen, Depo-Estradiol, Divigel, Elestrin Pump, Estrasorb, EstroGel Pump, Evamist, Estrace, DepoEstradiol, Elestrin, Estradot, Estrogel, Femtrace, Femring, Gynodiol

Synonyms: n.a.

What is Estra Pellets?

Nutropin AQ NuSpin 10

Generic Name: somatropin

Brand name: Genotropin, Humatrope, Norditropin FlexPro Pen, Nutropin AQ NuSpin 10, Nutropin AQ Pen 10 Cartridge, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, Genotropin Miniquick, Norditropin Nordiflex Pen, Tev-Tropin, Nutropin, Norditropin, Nutropin AQ, Nutropin Depot, Norditropin Cartridge, Saizen Click-Easy, Omnitrope Pen 5 Cartridge, HumatroPen, Omnitrope Pen 10 Cartridge, Nutropin AQ Pen 20 Cartridge, Nutropin AQ NuSpin 5, Nutropin AQ NuSpin 20, Saizen Kit

Synonyms: Nutropin AQ

What is Nutropin AQ NuSpin 10?