Estrace Cream and Etanercept

• Generic Name: estradiol topical
• Dosage Forms: vaginal cream
• Other Brand Names: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.

Some estradiol products placed directly into the vagina are used for "local" treatment of vaginal menopause symptoms (such as dryness, burning, and irritation). Other vaginal estradiol products are used for treating vaginal menopause symptoms and symptoms that affect other parts of the body (such as hot flashes). This type of vaginal estradiol has "systemic" effects, meaning that it can affect parts of the body other than where the medicine is directly applied.

This medication guide provides information about Estrace Vaginal for local treatment of vaginal symptoms of menopause (such as dryness, itching, irritation, and pain during sexual intercourse).

Estrace Vaginal (local) may also be used for purposes not listed in this medication guide.

• Generic Name: etanercept
• Dosage Forms: n.a.
• Other Brand Names: Enbrel, Erelzi Prefilled Syringe, Erelzi Sensoready Pen, Enbrel SureClick, Enbrel Prefilled Syringe, Enbrel Mini Prefilled Cartridge

Etanercept is a tumor necrosis factor (TNF) blocker that is used to treat:

• rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis, and to prevent joint damage caused by these conditions;

• polyarticular juvenile idiopathic arthritis in children who are at least 2 years old; and

• plaque psoriasis in adults and children who are at least 4 years old.

Etanercept may also be used for purposes not listed in this medication guide.