Estrace Cream and Otrexup injection

• Generic Name: estradiol topical
• Dosage Forms: vaginal cream
• Other Brand Names: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.

Some estradiol products placed directly into the vagina are used for "local" treatment of vaginal menopause symptoms (such as dryness, burning, and irritation). Other vaginal estradiol products are used for treating vaginal menopause symptoms and symptoms that affect other parts of the body (such as hot flashes). This type of vaginal estradiol has "systemic" effects, meaning that it can affect parts of the body other than where the medicine is directly applied.

This medication guide provides information about Estrace Vaginal for local treatment of vaginal symptoms of menopause (such as dryness, itching, irritation, and pain during sexual intercourse).

Estrace Vaginal (local) may also be used for purposes not listed in this medication guide.

• Generic Name: methotrexate
• Dosage Forms: injection, solution
• Other Brand Names: Methotrexate Sodium, Preservative Free, Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall, Xatmep

Otrexup interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Otrexup is used to treat leukemia and certain types of cancer of the breast, skin, head and neck, or lung. This medicine is also used to treat severe psoriasis and rheumatoid arthritis.

Otrexup is usually given after other treatments have failed.

Otrexup may also be used for purposes not listed in this medication guide.