Estrace Cream and Trexall

• Generic Name: estradiol topical
• Dosage Forms: vaginal cream
• Other Brand Names: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.

Some estradiol products placed directly into the vagina are used for "local" treatment of vaginal menopause symptoms (such as dryness, burning, and irritation). Other vaginal estradiol products are used for treating vaginal menopause symptoms and symptoms that affect other parts of the body (such as hot flashes). This type of vaginal estradiol has "systemic" effects, meaning that it can affect parts of the body other than where the medicine is directly applied.

This medication guide provides information about Estrace Vaginal for local treatment of vaginal symptoms of menopause (such as dryness, itching, irritation, and pain during sexual intercourse).

Estrace Vaginal (local) may also be used for purposes not listed in this medication guide.

• Generic Name: methotrexate
• Dosage Forms: tablet, film coated
• Other Brand Names: Rheumatrex Dose Pack, Trexall, Xatmep, Otrexup, Rasuvo, Methotrexate Sodium, Preservative Free

Trexall interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Trexall is used to treat certain types of cancer of the breast, skin, head and neck, or lung. This medicine is also used to treat severe psoriasis and rheumatoid arthritis.

Trexall is usually given after other medications have been tried without successful treatment of symptoms.

Trexall may also be used for purposes not listed in this medication guide.