Estradiol and Levonorgestrel and Raloxifene Hydrochloride
Determining the interaction of Estradiol and Levonorgestrel and Raloxifene Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using raloxifene together with estradiol. Both medications may have similar effects on certain tissues in the body. Therefore, combining them may increase the risk of side effects such as blood clots, stroke, and some cancers. You should seek immediate medical attention if you experience chest pain, shortness of breath, and/or pain or swelling in the arms or legs during treatment with either medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The concurrent use of raloxifene and systemic estrogen or hormone replacement therapy has not been evaluated in prospective clinical trials. Safety and efficacy of this combination are unknown. However, concomitant use of vaginal estrogen preparations was allowed in clinical trials for treatment of atrophic vaginal symptoms if necessary.
MANAGEMENT: Due to the lack of clinical data, use of raloxifene with systemic estrogens is not recommended.
- "Product Information. Evista (raloxifene)." Lilly, Eli and Company, Indianapolis, IN.
Generic Name: estradiol / levonorgestrel
Brand name: Climara Pro
Synonyms: Estradiol and levonorgestrel (transdermal)
Generic Name: raloxifene
Brand name: Evista
Synonyms: Raloxifene
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Estradiol and Levonorgestrel-Raloxifene Hydrochloride Tablets
- Estradiol and Levonorgestrel-Raltegravir
- Estradiol and Levonorgestrel-Raltegravir Chewable Tablets
- Estradiol and Levonorgestrel-Raltegravir Potassium
- Estradiol and Levonorgestrel-Raltegravir Powder for Oral Suspension
- Estradiol and Levonorgestrel-Raltegravir Tablets
- Raloxifene Hydrochloride-Estradiol and levonorgestrel transdermal
- Raloxifene Hydrochloride-Estradiol and medroxyprogesterone Intramuscular
- Raloxifene Hydrochloride-Estradiol and norethindrone
- Raloxifene Hydrochloride-Estradiol and Norethindrone Patch
- Raloxifene Hydrochloride-Estradiol and Norethindrone Tablets
- Raloxifene Hydrochloride-Estradiol and norethindrone transdermal