Estradiol and norgestimate and Lazanda
Determining the interaction of Estradiol and norgestimate and Lazanda and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration of fentanyl with other drugs, such as estrogens, that are also metabolized by CYP450 may theoretically result in elevated plasma concentrations of fentanyl and/or the coadministered drug(s). The mechanism is decreased drug clearance due to competitive inhibition of CYP450 activity. Although clinical data are lacking, the possibility of prolonged and/or increased pharmacologic effects of the drugs should be considered.
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: estradiol / norgestimate
Brand name: Prefest, Ortho-Prefest
Synonyms: Estradiol and Norgestimate
Generic Name: fentanyl
Brand name: Lazanda, Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Onsolis, Sublimaze
Synonyms: Lazanda Nasal Spray
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Estradiol and norgestimate-Lazanda Nasal Spray
- Estradiol and norgestimate-Leader Acid Control
- Estradiol and norgestimate-Leader Acid Reducer Maximum Strength
- Estradiol and norgestimate-Leader All Day Allergy
- Estradiol and norgestimate-Leader Allergy D 12
- Estradiol and norgestimate-Leader Allergy Relief
- Lazanda-Estradiol and progesterone
- Lazanda-Estradiol Gel (Divigel)
- Lazanda-Estradiol Gel (Elestrin)
- Lazanda-Estradiol Gel (EstroGel)
- Lazanda-Estradiol injection
- Lazanda-Estradiol Oral Tablets