Estradiol Gel (EstroGel) and Ribociclib and Letrozole
Determining the interaction of Estradiol Gel (EstroGel) and Ribociclib and Letrozole and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using estradiol together with letrozole. Using these medications together can make letrozole less effective. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Theoretically, estrogen-containing drugs may negate the pharmacologic effects of aromatase inhibitors in the treatment of hormone-dependent breast cancer. Aromatase inhibitors induce a state of estrogen deprivation in postmenopausal women by inhibiting the conversion of androgens to estrogens in adrenal and ovarian tissues, thus estrogen administration would be expected to reverse their therapeutic effects.
MANAGEMENT: Use of estrogen-containing products should be avoided during aromatase inhibitor therapy.
- "Product Information. Aromasin (exemestane)" Pharmacia & Upjohn, Kalamazoo, MI.
- "Product Information. Femara (letrozole)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Arimidex (anastrozole)." Zeneca Pharmaceuticals, Wilmington, DE.
Generic Name: estradiol
Brand name: Estrace, Vivelle-Dot, Vivelle, Delestrogen, DepoEstradiol, Divigel, Elestrin, Alora, Estraderm, Estradot, Estrasorb, Estrogel, Evamist, Femtrace, Menostar, Minivelle, Climara, Estradiol Patch, Depo-Estradiol, Elestrin Pump, EstroGel Pump, Femring, Gynodiol
Synonyms: Estradiol, Estradiol (Systemic)
Generic Name: letrozole / ribociclib
Brand name: Kisqali Femara Co-Pack 200 mg-25 mg Dose, Kisqali Femara Co-Pack 400 mg-25 mg Dose, Kisqali Femara Co-Pack 600 mg-25 mg Dose
Synonyms: Letrozole and ribociclib
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Estradiol Gel (EstroGel)-Ribociclib Succinate
- Estradiol Gel (EstroGel)-Rid-A-Pain Topical
- Estradiol Gel (EstroGel)-Ridactate
- Estradiol Gel (EstroGel)-Ridaura
- Estradiol Gel (EstroGel)-Rifabutin
- Estradiol Gel (EstroGel)-Rifadin
- Ribociclib and Letrozole-Estradiol injection
- Ribociclib and Letrozole-Estradiol Oral Tablets
- Ribociclib and Letrozole-Estradiol Patch
- Ribociclib and Letrozole-Estradiol topical for use on skin
- Ribociclib and Letrozole-Estradiol transdermal
- Ribociclib and Letrozole-Estradiol Transdermal Biweekly Patch