Estramustine Phosphate Sodium and Topcare Complete Acid Reducer plus Antacid
Determining the interaction of Estramustine Phosphate Sodium and Topcare Complete Acid Reducer plus Antacid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using calcium carbonate together with estramustine may decrease the effects of estramustine. Administration of estramustine should be separated at least 1 hour before or 2 hours after meals, milk, or calcium carbonate. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Oral calcium containing products may significantly decrease serum concentrations of estramustine. The mechanism of the interaction is not known.
MANAGEMENT: Estramustine should be taken at least 1 hour before or 2 hours after meals, milk, or calcium containing products.
- "Product Information. Emcyt (estramustine)." Pharmacia and Upjohn, Kalamazoo, MI.
Generic Name: estramustine
Brand name: Emcyt
Synonyms: Estramustine
Generic Name: calcium carbonate / famotidine / magnesium hydroxide
Brand name: Dual Action Complete, Duo Fusion, Pepcid Complete
Synonyms: Care One Acid Reducer Plus Antacid
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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