Estring Vaginal Ring and Imbruvica

• Generic Name: estradiol topical
• Dosage Forms: n.a.
• Other Brand Names: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy

Estring vaginal rings contain estradiol. Estradiol (a form of estrogen) is a female sex hormone necessary for many processes in the body. Estring releases estrogen that is absorbed directly through the skin of the vaginal wall.

Estring is used after menopause to treat moderate to severe menopausal changes in and around the vaginal area such as as dryness, burning, and itching of the vaginal area, urgency or irritation with urination, and pain during sexual intercourse).

Estring is an off-white, soft, flexible ring with a center that contains 2 mg of estradiol. The ring releases estradiol into the vagina in a consistent, stable manner for 90 days. It should be removed after 90 days of continuous use. If continued therapy is required, the ring should be replaced.

• Generic Name: ibrutinib
• Dosage Forms: capsule
• Other Brand Names: Imbruvica

Imbruvica (ibrutinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Imbruvica is used to treat mantle cell lymphoma, marginal zone lymphoma, Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, and small lymphocytic lymphoma. This medicine is also used to treat chronic graft-versus-host disease.

Imbruvica is usually given after other treatments have have not been effective.

Imbruvica was approved to treat mantle cell and marginal lymphomas by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.