Estring Vaginal Ring and Lorcaserin Hydrochloride

• Generic Name: estradiol topical
• Dosage Forms: n.a.
• Other Brand Names: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy

Estring vaginal rings contain estradiol. Estradiol (a form of estrogen) is a female sex hormone necessary for many processes in the body. Estring releases estrogen that is absorbed directly through the skin of the vaginal wall.

Estring is used after menopause to treat moderate to severe menopausal changes in and around the vaginal area such as as dryness, burning, and itching of the vaginal area, urgency or irritation with urination, and pain during sexual intercourse).

Estring is an off-white, soft, flexible ring with a center that contains 2 mg of estradiol. The ring releases estradiol into the vagina in a consistent, stable manner for 90 days. It should be removed after 90 days of continuous use. If continued therapy is required, the ring should be replaced.

• Generic Name: lorcaserin
• Dosage Forms: n.a.
• Other Brand Names: Belviq, Belviq XR

Adjunct to caloric restriction and increased physical activity in the chronic management of obesity.

Used in patients who are obese (pretreatment body mass index [BMI] ≥30 kg/m2); also used in overweight patients with pretreatment BMI ≥27 kg/m2 in the presence of a weight-related risk factor or disease (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia).

Indicated only for monotherapy; safety and efficacy in combination with other weight loss products (prescription drugs [e.g., phentermine], OTC drugs, herbal preparations) not established.

Long-term effects on cardiovascular morbidity and mortality associated with obesity not established; safety and efficacy beyond 2 years of use not established.