Etanercept and Letairis

• Generic Name: etanercept
• Dosage Forms: n.a.
• Other Brand Names: Enbrel, Erelzi Prefilled Syringe, Erelzi Sensoready Pen, Enbrel SureClick, Enbrel Prefilled Syringe, Enbrel Mini Prefilled Cartridge

Etanercept is a tumor necrosis factor (TNF) blocker that is used to treat:

• rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis, and to prevent joint damage caused by these conditions;

• polyarticular juvenile idiopathic arthritis in children who are at least 2 years old; and

• plaque psoriasis in adults and children who are at least 4 years old.

Etanercept may also be used for purposes not listed in this medication guide.

• Generic Name: ambrisentan
• Dosage Forms: tablet, film coated
• Other Brand Names: Letairis

Letairis (ambrisentan) prevents thickening of the blood vessels, especially those in the lungs and heart. Ambrisentan also lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

Letairis is used to treat pulmonary arterial hypertension (PAH) in adults. It improves your ability to exercise and prevents your condition from getting worse.

Letairis is sometimes used with a medicine called tadalafil (Adcirca).

For women, Letairis is available only from a certified pharmacy under a special program. You must be registered in the program and sign agreements to use birth control and undergo pregnancy and blood testing.