Ethinyl estradiol and desogestrel and Saquinavir
Determining the interaction of Ethinyl estradiol and desogestrel and Saquinavir and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Saquinavir may reduce the blood levels and effects of ethinyl estradiol. If you are using ethinyl estradiol for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. You may need an alternative or additional method of birth control during or after treatment with saquinavir in order to avoid an unintended pregnancy. Let your doctor know if you experience bleeding outside of your menstrual cycle, since it may indicate reduced effectiveness of ethinyl estradiol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADDITIONAL CONTRACEPTION RECOMMENDED: Coadministration with saquinavir-ritonavir may decrease the plasma concentrations of estrogen-containing oral contraceptives. The precise mechanism of interaction is unknown but may involve hepatic enzyme induction.
MANAGEMENT: Women using oral contraceptives should be advised of the risk of breakthrough bleeding and unintended pregnancy during concomitant therapy with ritonavir. Alternative or additional methods of birth control should be used during concomitant therapy with saquinavir-ritonavir.
- "Product Information. Invirase (saquinavir)." Roche Laboratories, Nutley, NJ.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: desogestrel / ethinyl estradiol
Brand name: Azurette, Cyclessa, Desogen, Isibloom, Kariva, Mircette, Reclipsen, Cyred
Synonyms: Ethinyl Estradiol and Desogestrel
Generic Name: saquinavir
Brand name: Invirase, Fortovase
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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